Shuofeng Yuan Selected Research

Virus Diseases (Viral Diseases)

3/2024	PMI-controlled mannose metabolism and glycosylation determines tissue tolerance and virus fitness.
1/2023	Neutralisation of SARS-CoV-2 by monoclonal antibody through dual targeting powder formulation.
12/2022	hnRNP C modulates MERS-CoV and SARS-CoV-2 replication by governing the expression of a subset of circRNAs and cognitive mRNAs.
7/2022	Metal-based strategies for the fight against COVID-19.
2/2022	Orally administered bismuth drug together with N-acetyl cysteine as a broad-spectrum anti-coronavirus cocktail therapy.
4/2021	A new class of α-ketoamide derivatives with potent anticancer and anti-SARS-CoV-2 activities.
1/2021	Robust SARS-CoV-2 infection in nasal turbinates after treatment with systemic neutralizing antibodies.
1/2021	Clofazimine broadly inhibits coronaviruses including SARS-CoV-2.
12/2020	Competing endogenous RNA network profiling reveals novel host dependency factors required for MERS-CoV propagation.
10/2020	Clofazimine is a broad-spectrum coronavirus inhibitor that antagonizes SARS-CoV-2 replication in primary human cell culture and hamsters.

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Shuofeng Yuan Research Topics

Disease

38	COVID-19 04/2024 - 01/2020
34	Infections 04/2024 - 09/2012
14	Virus Diseases (Viral Diseases) 03/2024 - 01/2019
12	Human Influenza (Influenza) 05/2022 - 01/2016
6	Inflammation (Inflammations) 04/2024 - 01/2021
5	Pneumonia (Pneumonitis) 01/2023 - 11/2020
5	Body Weight (Weight, Body) 01/2022 - 12/2018
3	Reinfection 11/2021 - 01/2021
2	Cytokine Release Syndrome 01/2024 - 10/2020
2	Severe Acute Respiratory Syndrome 12/2023 - 05/2022
2	Adenocarcinoma of Lung 12/2022 - 12/2020
2	Melanoma (Melanoma, Malignant) 08/2022 - 01/2019
2	Weight Loss (Weight Reduction) 01/2021 - 12/2020
2	Leprosy (Hansen's Disease) 01/2021 - 10/2020
2	Influenza in Birds (Avian Flu) 01/2018 - 11/2016
2	Zika Virus Infection 09/2017 - 01/2017
1	Hypoxia (Hypoxemia) 03/2024
1	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 11/2023
1	Diarrhea 11/2023
1	Communicable Diseases (Infectious Diseases) 10/2023
1	Respiratory Tract Infections (Respiratory Tract Infection) 05/2022
1	Myalgia 01/2022
1	Bites and Stings (Sting) 01/2022
1	Neoplasms (Cancer) 04/2021
1	Hematologic Neoplasms (Hematological Malignancy) 04/2021

Drug/Important Bio-Agent (IBA)

27	Antiviral Agents (Antivirals)IBA 04/2024 - 07/2015
10	Proteins (Proteins, Gene)FDA Link 04/2024 - 11/2016
9	VaccinesIBA 04/2024 - 01/2019
6	CytokinesIBA 04/2024 - 12/2020
6	N-(2-cyanoethylene)urea (BA 1)IBA 10/2023 - 01/2022
5	Neutralizing AntibodiesIBA 12/2023 - 01/2021
4	Immunoglobulin G (IgG)IBA 03/2022 - 01/2021
4	LipidsIBA 01/2022 - 01/2019
4	ChemokinesIBA 01/2022 - 12/2020
3	Biomarkers (Surrogate Marker)IBA 04/2024 - 03/2022
3	Monoclonal AntibodiesIBA 10/2023 - 01/2023
3	MetalsIBA 10/2023 - 03/2022
3	N-methyl-valyl-amiclenomycin (BA 2)IBA 09/2023 - 01/2022
3	Serine Proteases (Serine Protease)IBA 01/2023 - 01/2018
3	DNA (Deoxyribonucleic Acid)IBA 01/2023 - 03/2016
3	remdesivirIBA 12/2021 - 10/2020
2	RNA (Ribonucleic Acid)IBA 01/2024 - 12/2018
2	InterferonsIBA 01/2024 - 10/2020
2	Small Interfering RNA (siRNA)IBA 01/2024 - 12/2022
2	Immunoglobulin A (IgA)IBA 12/2023 - 03/2022
2	Viral AntigensIBA 09/2023 - 01/2021
2	PowdersIBA 01/2023 - 05/2022
2	SARS-CoV-2 spike proteinIBA 01/2023 - 12/2021
2	Peptide Hydrolases (Proteases)FDA Link 01/2023 - 12/2022
2	Inactivated VaccinesIBA 01/2023 - 01/2022
2	AntigensIBA 01/2023 - 09/2012
2	Messenger RNA (mRNA)IBA 12/2022 - 12/2020
2	Circular RNAIBA 12/2022 - 12/2020
2	Hemagglutinins (Hemagglutinin)IBA 11/2022 - 01/2017
2	TNF Receptor-Associated Factor 3IBA 01/2022 - 01/2019
2	C-Reactive ProteinIBA 11/2021 - 01/2020
2	Nucleocapsid ProteinsIBA 10/2021 - 12/2020
2	NucleoproteinsIBA 01/2021 - 01/2021
2	Clofazimine (Lamprene)FDA Link 01/2021 - 10/2020
2	Arachidonic Acid (Vitamin F)IBA 11/2019 - 01/2019
2	EndonucleasesIBA 03/2016 - 07/2015
2	Zanamivir (Relenza)FDA Link 03/2016 - 01/2016
1	Interleukin-10 (Interleukin 10)IBA 04/2024
1	Transferrin (beta 2 Transferrin)IBA 04/2024
1	Chelating AgentsIBA 04/2024
1	IronIBA 04/2024
1	Mannose (D-Mannose)IBA 03/2024
1	Succinic Acid (Succinate)IBA 03/2024
1	Reactive Oxygen Species (Oxygen Radicals)IBA 03/2024
1	COVID-19 VaccinesIBA 11/2023
1	Serotonin (5 Hydroxytryptamine)IBA 11/2023
1	SeleniumIBA 10/2023
1	alisol B 23-acetateIBA 10/2023
1	Matrix Metalloproteinase 14 (MT1-MMP)IBA 12/2022
1	RNA-Binding Proteins (RNA-Binding Protein)IBA 12/2022
1	Heterogeneous-Nuclear Ribonucleoproteins (Informatin)IBA 12/2022
1	LectinsIBA 10/2022
1	VemurafenibIBA 08/2022
1	IonsIBA 07/2022
1	Anti-Infective Agents (Microbicides)IBA 05/2022
1	RetinoidsIBA 05/2022
1	tamibaroteneIBA 05/2022
1	AntibodiesIBA 03/2022
1	MMDAIBA 03/2022
1	Angiotensin-Converting Enzyme 2IBA 01/2022
1	CalciumIBA 01/2022
1	ManganeseIBA 01/2022
1	Caspase 6IBA 01/2022
1	Subunit VaccinesIBA 01/2022
1	Methylprednisolone FDA LinkGeneric 12/2021
1	Immunodominant EpitopesIBA 12/2021
1	Viral ProteinsIBA 12/2021
1	Ligases (Synthetase)IBA 10/2021
1	Triglycerides (Triacylglycerol)IBA 10/2021
1	xanthohumolIBA 10/2021
1	Proteasome Endopeptidase Complex (Proteasome)IBA 04/2021

Therapy/Procedure

13	Therapeutics 04/2024 - 01/2016
2	Intranasal Administration 02/2024 - 05/2022
2	Oral Administration 01/2023 - 02/2022
1	Subcutaneous Injections 12/2021